Gopher Prairie, a bastion of prosaic, small-minded, middle-class values. Its newest inhabitant is the beautiful young college graduate Carol Milford moves from the city to tiny Gopher Prairie after marrying the local doctor, and tries to bring culture to the small town. But Carol is no match for the town's provincialism, and her struggle to overcome the complacency, bigotry, and hypocrisy of Gopher Prairie becomes author's devastating and satiric take on all small towns.
Lewis's portrayal of a marriage torn by disillusionment and a woman forced into compromises is at once devastating social satire and persuasive realism. His subtle characterisations and intimate details of small-town America make Main Street a complex and compelling work established Lewis as an important figure in twentieth-century American Literature.